I don't think it's homophobic so much as its taboo or not necessarily "run of the mill". I think the effect would have been about the same if she'd said he liked having his toes sucked or his nipples tweaked or whatever.
For context, and I think this is especially relevant for camgirls, Amber Rose is Kanye's ex girlfriend and a former stripper. This tweet was in response to him (once again) bringing up her stripper past to shame her. He was trying to pick a fight with her ex-boyfriend and was going off about how the ex got "trapped by a stripper" and how when the ex looked at his child with Amber he must be sad that it would always remind him of the stripper who trapped him.
Kanye (who is married with two kids) is constantly bringing up Amber and trying to shame her for being a stripper. I didn't read this as homophobic (or ~kink shaming~) at all, so much as Amber getting pissed off at being dragged into this again and trying to embarrass him by airing his sexual laundry. What people make of that is their own business (thinking its gay, or like me just being like "teehee Kanye sex secret"). I don't see it as any worse than his "ew a stripper" rhetoric. i feel bad that she keeps getting dragged into this, let alone her child, where its pretty unequal (he has 17m Twitter followers, this isn't like my exes ranting to their friends at a bar, she is pulled into the situation whether she wants to be or not). It seems like a crummy situation for her.
I love Kanye's music and used to think he was just quirky and egotistical but so many instances over the past few years have shown he's really just a fucking douche.